Restore to Localhost ->ASP.NET Ajax client-side framework failed to load.

Hi Chad,
Have you repairing or upgrade .net hotfix lately? Check if this blog ease up your issue.
http://geekswithblogs.net/WillSmith/archive/2008/12/11/resolving-asp.net-ajax-client-side-framework-failed-to-load.aspx

I thought that it was a problem about wrong asp.net ajax version but looking around I found that could be a permissions problem as explained in this http://forums.asp.net/t/1489077.aspx, even if is not directly connected to DotnetNuke, i think could be usefull.

Paolo.

@Paolo: i've already looked into that solution and it wasn't that. My DNN webconfig doesn't restrict access to all users.

@x_com: I did recently upgrade asp.net framework from 3.5 to 4. But I don't the re-install is the fix as I have another instance of DNN running on this same machine and it works fine. I'm guessing it has something to do with it's webconfig file.

More Info:

Here's the exact section. It goes within the <system.webServer> section.
    <handlers>
      <remove name="WebServiceHandlerFactory-Integrated" />
      <add name="LogoffHandler*" path="Logoff.aspx" verb="*" type="DotNetNuke.Services.Authentication.LogOffHandler, DotNetNuke" preCondition="integratedMode,runtimeVersionv2.0" />
      <add name="RSSHandler" path="RSS.aspx" verb="*" type="DotNetNuke.Services.Syndication.RssHandler, DotNetNuke" preCondition="integratedMode,runtimeVersionv2.0" />
      <add name="LinkClickHandler" path="LinkClick.aspx" verb="*" type="DotNetNuke.Services.FileSystem.FileServerHandler, DotNetNuke" preCondition="integratedMode,runtimeVersionv2.0" />
      <add name="CaptchaHandler" path="*.captcha.aspx" verb="*" type="DotNetNuke.UI.WebControls.CaptchaHandler, DotNetNuke" preCondition="integratedMode,runtimeVersionv2.0" />
      <add name="ScriptHandlerFactory" verb="*" path="*.asmx" preCondition="integratedMode" type="System.Web.Script.Services.ScriptHandlerFactory, System.Web.Extensions, Version=3.5.0.0, Culture=neutral, PublicKeyToken=31BF3856AD364E35" />
      <add name="ScriptHandlerFactoryAppServices" verb="*" path="*_AppService.axd" preCondition="integratedMode" type="System.Web.Script.Services.ScriptHandlerFactory, System.Web.Extensions, Version=3.5.0.0, Culture=neutral, PublicKeyToken=31BF3856AD364E35" />
      <add name="ScriptResource" verb="GET,HEAD" path="ScriptResource.axd" preCondition="integratedMode" type="System.Web.Handlers.ScriptResourceHandler, System.Web.Extensions, Version=3.5.0.0, Culture=neutral, PublicKeyToken=31BF3856AD364E35" />
      <add name="UserProfilePageHandler" verb="*" path="User.aspx" type="DotNetNuke.Services.UserProfile.UserProfilePageHandler, DotNetNuke" preCondition="integratedMode,runtimeVersionv2.0" />
      <add name="RadProgressHandler" verb="*" path="Telerik.RadUploadProgressHandler.ashx" type="Telerik.Web.UI.Upload.RadUploadProgressHandler, Telerik.Web.UI" preCondition="integratedMode" />
      <add name="Telerik.Web.UI.WebResource" verb="*" path="Telerik.Web.UI.WebResource.axd" type="Telerik.Web.UI.WebResource, Telerik.Web.UI" />
      <add name="Telerik.Web.UI.ChartHttpHandler" verb="*" path="ChartImage.axd" type="Telerik.Web.UI.ChartHttpHandler, Telerik.Web.UI, Culture=neutral, PublicKeyToken=121fae78165ba3d4" />
      <add name="SitemapHandler" path="Sitemap.aspx" verb="*" type="DotNetNuke.Services.Sitemap.SitemapHandler, DotNetNuke" preCondition="integratedMode,runtimeVersionv2.0" />
      <add name="HtmTemplateFileHandler" verb="*" path="*.htmtemplate" type="DotNetNuke.HtmlEditor.TelerikEditorProvider.HtmTemplateFileHandler, DotNetNuke.HtmlEditor.TelerikEditorProvider" preCondition="integratedMode" />
    </handlers>
Hope this helps someone else!

Thanks for sharing your final outcome with us, chad.

SOLVED