PHP Regex for mixed quantities of consecutive characters

Hi all,

I want to match varying quantities of consecutive characters in a string.  
For example, in $string I want to replace with nothing (i.e. ""):
any number of instances (consecutive or not) of !@#
and replace instances of 2 or more consecutive -
and replace instances of 3 or more consecutive +

Example:
$string='d+++og! + ca#t@ - how about the m--ule';
 I'd like to do something like:
echo preg_replace("/[!@#(\-{2,})(\+{3,})]/","",$string);
to get "dog + cat - how about the mule"

Every variant of moving/removing the parentheses and brackets that I've tried replaces either all instances of - and + including where they only occur once, or replaces no instances at all.

Thank you in advance.