We are experiencing a few odd issues on some systems that we believe we have narrowed down to an issue that Microsoft has issued a hotfix for. However, we are typically hesitant to install hotfixes as Microsoft's warning on them says only to install them if we are "greatly effected by the problem." That's really hard to say,as compared to what? It goes on to say that the fix might undergo additional testing and updates before it shows up in the next service pack. Typical hotfix lingo.
Regardless, what is your experience with hotfixes? Do you typically install them, or wait for the next service pack to include them?