I just got done solving a desktop icon arrangement issue by unchecking the "Align icons to grid" option, and the first time I rebooted and replied to an e-mail in Outlook, the signature I have set up for business did not properly display. I can't imagine how the 2 are related but I find it coincidental.
I'm using Windows 7. What happened was I set up a business signature which included 2 hyperlinks. After replying to an e-mail, All the text information displays, but the hyperlinks are gone. I double checked the settings for the signature (see attached file) and it seems fine.