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Try the troubleshooting steps here:<br />
<br />
<a href="http://support.microsoft.com/kb/921541" rel="ugc">http://support.microsoft.com/kb/921541</a>
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Try the troubleshooting steps here:

http://support.microsoft.com/kb/921541 [http://support.microsoft.com/kb/921541]

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I would uninstall then reinstall
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I found this link very helpful for myself, I hope it helps you too.<br />
<a href="http://word.tips.net/Pages/T000316_Cant_Open_a_Word_Document_in_Windows.html" rel="ugc">http://word.tips.net/Pages/T000316_Cant_Open_a_Word_Document_in_Windows.html</a>
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I found this link very helpful for myself, I hope it helps you too.
http://word.tips.net/Pages/T000316_Cant_Open_a_Word_Document_in_Windows.html [http://word.tips.net/Pages/T000316_Cant_Open_a_Word_Document_in_Windows.html]

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It's a workaround - hopefully Microsoft will fix this issue. &nbsp;I found this fix outside of Experts Exchange.
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It's a workaround - hopefully Microsoft will fix this issue.  I found this fix outside of Experts Exchange.

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<div class="content wysiwyg-content">
We have updated some of our Windows XP machines to Office 2010 and we have a couple users reporting from Windows Explorer, that when they double-click on a Word document in Word 2010, it looks like Word tries to open but then &quot;poofs away&quot; without opening itsellf and the document. &nbsp;<b>Is there any fix for this? &nbsp;</b> Opening the document via starting Word and doing File -&gt; Open does seem to work. &nbsp; One user reported a file was corrupted but could be opened on another machine.
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We have updated some of our Windows XP machines to Office 2010 and we have a couple users reporting from Windows Explorer, that when they double-click on a Word document in Word 2010, it looks like Word tries to open but then "poofs away" without opening itsellf and the document.  Is there any fix for this?   Opening the document via starting Word and doing File -> Open does seem to work.   One user reported a file was corrupted but could be opened on another machine.

Word 2010 won't open document from Explorer on XP PC

Microsoft Word is a commercial document editing program that is part of the Microsoft Office suite. It features numerous text-editing tools for creating richly formatted documents, along with tools for the use of macros in Word documents. Word's native file formats are denoted either by a .doc or .docx file extension. Plugins permitting the Windows versions of Word to read and write formats it does not natively support, such as the OpenDocument format (ODF) are available. Word can import and display images in common bitmap formats such as JPG and GIF. It can also be used to create and display simple line-art.

Microsoft Word

Microsoft Windows XP is the sixth release of the NT series of operating systems, and was the first to be marketed in a variety of editions: XP Home and XP Professional, designed for business and power users. The advanced features in XP Professional are generally disabled in Home Edition, but are there and can be activated. There were two 64-bit editions, an embedded edition and a tablet edition.

Windows XP

A personal computer is a general-purpose computer whose size, capabilities and price make it useful for individuals, and is intended to be operated directly by an end-user with no intervening computer time-sharing models that allowed systems to be used by many people, usually at the same time. Personal computers may be connected to a local area network (LAN), either by a cable or a wireless connection, and through that to the Internet. A personal computer may be a laptop computer or a desktop computer running an operating system such as Windows, Linux or Macintosh OS.