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Exchange 2010 take up to 10 sec to delete messages or view one

We recently migrate our Exchange 2003 server to an Exchange 2010 server. We still have the 2003 running because the mailboxes are not yet moved. The new server is a Windows 2008 R2 (64 bits) with Exchange 2010 (version 14.01.0270.001) installed on. We installed Rollup 1 and 2 on it and we have Nod32 as antivirus. We had installed MS Forefront but it cause a lot of problem so we’re back to Nod32.

 The problem is that we experienced slow transaction in the mailboxes that are on the Exchange 2010 server with any Outlook version (2003 and 2007). The client who experienced the most problem has a 4.5 Gb mailboxes. Those who have a smaller mailbox seem to get fewer problems.

We’ve add a registry entry for the MSExchangeRPC/ParametersSystem/Maximum Polling Entry  because outlook 2003 could take up to 15 minutes to receive a message and it work pretty good for now.

In the Event viewer, i have this error:
Couldn't find an Exchange 2010 or later public folder server with a replica for the free/busy folder:
But, may be it's because the Exchange 2003.

Thanks a lot.
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ASKER

How do I add the replicas to the Free busy folder? I don't see any Free busy folder except the SCHEDULE+ FREE BUSY
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ASKER

Is this command could resolve this:
.\MoveAllReplicas.ps1 -Server "oldMAILSRV" -NewServer "newMAIL"
You also have to check the autodiscovery configuration. In my case the free busy url was pointing to my old server instead of my new exchange server. After changing this with the management shell, everything seems to be fine again.
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ASKER

The responsiveness still extremely slow
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How did you change the autodiscovery ?