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Also if you have a router check the router logs for unusually numerous SMTP traffic, or port 25 traffic.
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Also if you have a router check the router logs for unusually numerous SMTP traffic, or port 25 traffic.

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Block the outbound SMTP connections from any system on your network with the exception of your internal relay server.<br />
This way you can look at the logs on your internal mail server and depending on the mail server you have, you could use/implement a mechanism that will curb the inordinate influx of outgoing emails from single source.
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Block the outbound SMTP connections from any system on your network with the exception of your internal relay server.
This way you can look at the logs on your internal mail server and depending on the mail server you have, you could use/implement a mechanism that will curb the inordinate influx of outgoing emails from single source.

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This question has been classified as abandoned and is being closed as part of the Cleanup Program. See my comment at the end of the question for more details.
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This question has been classified as abandoned and is being closed as part of the Cleanup Program. See my comment at the end of the question for more details.

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What is a good program to check network traffic, and be able to pick up on whether a computer is sending out Spam?
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What is a good program to check network traffic, and be able to pick up on whether a computer is sending out Spam?

How to check if a computer is sending out Spam

The Microsoft Legacy Operating System topic includes legacy versions of Microsoft operating systems prior to Windows 2000: All versions of MS-DOS and other versions developed for specific manufacturers and Windows 3/3.1, Windows 95 and Windows 98, plus any other Windows-related versions, and Windows Mobile.

Microsoft Legacy OS

A vulnerability is a weakness which allows an attacker to reduce a system's information assurance. Vulnerability is the intersection of three elements: a system susceptibility or flaw, attacker access to the flaw, and attacker capability to exploit the flaw. To exploit a vulnerability, an attacker must have at least one applicable tool or technique that can connect to a system weakness, known as the attack surface. Vulnerability management is the cyclical practice of identifying, classifying, remediating, and mitigating vulnerabilities. Other vulnerabilities include security risks, security defects and constructs in programming languages that are difficult to use properly.

Vulnerabilities

Spyware is software that aims to gather information about a person or organization without their knowledge and that may send such information to another entity without the consumer's consent, or that asserts control over a computer without the consumer's knowledge; it has also come to include programs that engage in various kinds of electronic fraud. Anti-spyware is software that removes or blocks that software; some common vendors include Malwarebytes, McAfee, Spybot-Search and Destroy, Ad-Aware and BitDefender.