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Is using external software an option, or do you want to do this using AD ?<br />
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If AD - you have two options 1) disable USB drives using GPO or 2) specifically allow all applications that you want to allow - anything not mentioned (i.e usb etc) will be blocked.
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Is using external software an option, or do you want to do this using AD ?

If AD - you have two options 1) disable USB drives using GPO or 2) specifically allow all applications that you want to allow - anything not mentioned (i.e usb etc) will be blocked.

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You can also do the above from a GPO.
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how to deny running portable softwares?
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how to deny running portable softwares?

Active Directory (AD) is a Microsoft brand for identity-related capabilities. In the on-premises world, Windows Server AD provides a set of identity capabilities and services, and is hugely popular (88% of Fortune 1000 and 95% of enterprises use AD). This topic includes all things Active Directory including DNS, Group Policy, DFS, troubleshooting, ADFS, and all other topics under the Microsoft AD and identity umbrella.

Active Directory

Operating system security (OS security) is the process of ensuring OS integrity, confidentiality and availability. OS security refers to specified steps or measures used to protect the OS from threats, viruses, worms, malware or remote hacker intrusions. OS security encompasses all preventive-control techniques, which safeguard any computer assets capable of being stolen, edited or deleted if OS security is compromised, including authentication, passwords and threats to systems and programs.

OS Security

File sharing is the practice of distributing or providing access to digital media, such as computer programs, multimedia (audio, images and video), documents or electronic books. Common methods of storage, transmission and dispersion include manual sharing utilizing removable media, centralized servers on computer networks, World Wide Web-based hyperlinked documents, distributed peer-to-peer networking (P2P) and cloud-based file syncing.