Netbackup Error "Network Read Failed(42)" When Backing up Exchange 2010

We have just implimented Exchange 2010 on two Windows 2008 R2 servers in a DAG cluster.  The servers are at different sites, the server at our main site is connected to our Equallogic iSCSI SAN while the server at our other site has local SCSI disks.  

We are using Netbackup 7.0.1 and when I initially setup the backups of Exchange with Netbackup it worked fine.  We have recently migrated our mail into Exchange and now we are having problems with the backup of the server at our main site, the backups are failing with a "network read failed(42)" error.

If anyone has any ideas on what may be causing this I would apprecaite them.

Thanks

Here is the information from Netbackup:

First Job (that creates the snapshot):
19/02/2011 1:04:18 PM - requesting resource Windows-DDR1
19/02/2011 1:04:18 PM - requesting resource cypress.NBU_CLIENT.MAXJOBS.EMPIRE
19/02/2011 1:04:18 PM - requesting resource cypress.NBU_POLICY.MAXJOBS.Exchange
19/02/2011 1:04:19 PM - granted resource cypress.NBU_CLIENT.MAXJOBS.EMPIRE
19/02/2011 1:04:19 PM - granted resource cypress.NBU_POLICY.MAXJOBS.Exchange
19/02/2011 1:04:19 PM - granted resource MediaID=@aaaam;Path=\\192.168.1.10\backup\Netbackup\Windows;MediaServer=cypress
19/02/2011 1:04:19 PM - granted resource Windows-DDR1
19/02/2011 1:04:20 PM - estimated 0 Kbytes needed
19/02/2011 1:04:20 PM - begin Parent Job
19/02/2011 1:04:20 PM - begin Unknown Type, Step By Condition
Status 0
19/02/2011 1:04:20 PM - end Unknown Type, Step By Condition; elapsed time: 00:00:00
19/02/2011 1:04:20 PM - begin Unknown Type, Read File List
Status 0
19/02/2011 1:04:20 PM - end Unknown Type, Read File List; elapsed time: 00:00:00
19/02/2011 1:04:20 PM - begin Unknown Type, Create Snapshot
19/02/2011 1:04:20 PM - started
19/02/2011 1:04:21 PM - started process bpbrm (16260)
19/02/2011 1:04:25 PM - begin Create Snapshot
19/02/2011 1:05:00 PM - Info bpbrm(pid=16260) from client EMPIRE: TRV - snapshot preparation successful    
19/02/2011 1:32:35 PM - Error bpbrm(pid=16260) from client EMPIRE: ERR - Send bpfis state from cypress failed. status = 25
19/02/2011 1:32:35 PM - end Create Snapshot; elapsed time: 00:28:10
19/02/2011 1:32:38 PM - end writing
Status 0
19/02/2011 1:32:38 PM - end Unknown Type, Create Snapshot; elapsed time: 00:28:18
19/02/2011 1:32:38 PM - begin Unknown Type, Policy Execution Manager Preprocessed
Status 42
19/02/2011 1:38:26 PM - end Unknown Type, Policy Execution Manager Preprocessed; elapsed time: 00:05:48
19/02/2011 1:38:26 PM - begin Unknown Type, Stop On Error
Status 0
19/02/2011 1:38:26 PM - end Unknown Type, Stop On Error; elapsed time: 00:00:00
19/02/2011 1:38:26 PM - begin Unknown Type, Delete Snapshot On Exit
19/02/2011 1:38:26 PM - begin Unknown Type, Delete Snapshot On Exit
19/02/2011 1:38:26 PM - started process bpbrm (18212)
19/02/2011 1:38:49 PM - end writing
Status 0
19/02/2011 1:38:49 PM - end Unknown Type, Delete Snapshot On Exit; elapsed time: 00:00:23
Status 42
19/02/2011 1:38:49 PM - end Unknown Type, Delete Snapshot On Exit; elapsed time: 00:00:23
network read failed(42)

Second Job (that performs the backup and is called by the first job):
19/02/2011 1:38:02 PM - requesting resource Windows-DDR1
19/02/2011 1:38:02 PM - requesting resource cypress.NBU_CLIENT.MAXJOBS.EMPIRE
19/02/2011 1:38:02 PM - requesting resource cypress.NBU_POLICY.MAXJOBS.Exchange
19/02/2011 1:38:02 PM - granted resource cypress.NBU_CLIENT.MAXJOBS.EMPIRE
19/02/2011 1:38:02 PM - granted resource cypress.NBU_POLICY.MAXJOBS.Exchange
19/02/2011 1:38:02 PM - granted resource MediaID=@aaaam;Path=\\192.168.1.10\backup\Netbackup\Windows;MediaServer=cypress
19/02/2011 1:38:02 PM - granted resource Windows-DDR1
19/02/2011 1:38:02 PM - estimated 0 Kbytes needed
19/02/2011 1:38:02 PM - started process bpbrm (16644)
19/02/2011 1:38:09 PM - connecting
19/02/2011 1:38:12 PM - connected; connect time: 00:00:03
19/02/2011 1:38:18 PM - Warning bptm(pid=16556) could not set TCP_NODELAY on socket 532, h_errno = 10038  
19/02/2011 1:38:19 PM - Warning bptm(pid=17804) could not set non-blocking on socket 532, An operation was attempted on something that is not a socket.
19/02/2011 1:38:19 PM - Error bptm(pid=17804) socket operation failed - 10038 (at child.c.1294)      
19/02/2011 1:38:19 PM - Error bptm(pid=17804) unable to perform read from client socket, connection may have been broken
19/02/2011 1:38:19 PM - begin writing
19/02/2011 1:38:26 PM - end writing; write time: 00:00:07
network read failed(42)