Strange mouse problem

I have a strange problem with my own computer.     It's an XP pro machine fully patched.     Every few days, my left mouse button acts like it is stuck down.      I can reboot my computer and make it go back to normal.    I have tried 4 different mice and the same problem that happens a few hours after reboot.    Any ideas?
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Gary Fuqua, CISSPOwnerAsked:
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Gary Fuqua, CISSPConnect With a Mentor OwnerAuthor Commented:
I finally figured out how to correct the problem, but I'm not sure what is doing it.     If I tap the shift key once, the mouse releases its grip on the selection.   I must have some underlying software that interprets a longer than usual shift hold as a shift lock.  
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thakurdineshCommented:
You need to uninstall the Mice driver and reinstall from device manager.

or you can go to device manager and roll back to previous version of driver and verify if it works..

Last resort I will suspect USB port, if this mice is USB based or PS2 port if mice is PS2 based.
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BDugasCommented:
If you are using any ps2 or usb adapter, it could be causing the problem
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Gary Fuqua, CISSPOwnerAuthor Commented:
The problem occurs with a PS2 or or USB mouse connected directly.    As I said, it's an odd problem.
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BDugasCommented:
It trully sounds like a driver, os, or malware issue... I would scan from safemode see what you find.. reinstall the driver.. then a system repair
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Gary Fuqua, CISSPOwnerAuthor Commented:
It's the standard mouse driver and has been reinstalled more than once to no avail.      No malware found with Trend Micro, malwarebytes, etc.
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cashewnutCommented:
Seem nothing wrong with the mouse, you better try to repair the window to try
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Gary Fuqua, CISSPOwnerAuthor Commented:
I found the solution.
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