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It will not break RP over https. OWA is independent from outlook anywhere 
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We would like to shut down OWA access to our exchange servers, but are wondering if it will break RPC over SSL on the few outlook remote clients we have. &nbsp;I have not been ableto find a definative answer.
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We would like to shut down OWA access to our exchange servers, but are wondering if it will break RPC over SSL on the few outlook remote clients we have.  I have not been ableto find a definative answer.

Can you still run RPC over SSL to your remote outlook clients without running OWA

Exchange is the server side of a collaborative application product that is part of the Microsoft Server infrastructure. Exchange's major features include email, calendaring, contacts and tasks, support for mobile and web-based access to information, and support for data storage.

Exchange

Microsoft Outlook is a personal information manager from Microsoft, available as a part of the Microsoft Office suite. Although often used mainly as an email application, it also includes a calendar, task manager, contact manager, note-taker, journal, and web browser.