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emails stuck in local delivery queue

Every few weeks one of my backend Exchange servers is getting emails stuck in the local delivery queue.  I don't seem to be having DNS issues for my other backend server uses the same local DNS servers.  Eventually if I force emails and restart serivces they'll eventually start to flow again.  I don't see any error in my event logs.  Any suggestions?
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gopher_49
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gopher_49
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Glen KnightCommented:
99 times out of 100 when this happens it's due to AntiVirus or SPAM software, the installs can often become corrupt with the hooks they use on the SMTP service but an update or something.

Easiest way to resolve it is to uninstall the AV or SPAM software, restart the server, check everything is working then re-install the AV/SPAM software
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gopher_49Author Commented:
I have VIPRE anti virus installed on the server.  All spam filtering is done on the frontend server. I just noew rebooted the server for I tried everything else.  I even tried shutting down the anti virus agent and that didn't help.  Once it comes back up I'll uninstall the anti virus software..  It's set to void all Exchange folders.  Real time scanning is disabled and all mail scanning features are disabled.
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Glen KnightCommented:
disabling the services will not help, it must be uninstalled.
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gopher_49Author Commented:
One user got the below message too..  Below the error where a series of recipeints how get copies of others emails...  

You do not have permission to send to this recipient.  For assistance, contact your system administrator.
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Glen KnightCommented:
that's a seperate issue, let's try and resolve this one first.
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gopher_49Author Commented:
I'm uninstalling the AV software now...  Emails are being help up in queue right now...
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gopher_49Author Commented:
The AV software is uninstalled and emails still stuck in queue.  I'll restart the SMTP service and we'll see what happens.
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Glen KnightCommented:
are there any errors on the queues? If you run a telnet test to the server following these instructions what happens:

http://support.microsoft.com/kb/153119
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gopher_49Author Commented:
actually.. It's still uninstalling for the CPU is showing alot of utilization on the msiexec.exe process.. I'll let it finish.
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gopher_49Author Commented:
I'm getting retry error in the queue.  I'll try the commands.
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gopher_49Author Commented:
ok..  All commands worked.. Also, emails are now coming out of queue now that the AV is off.. imagine that! I'll keep it off and contact the vendor.  Let's keep the ticket open just in case the problem comes back.
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Glen KnightCommented:
you will probably find that simply re-installing it will resolve the issue and your AV will be back on and mailflow will continue.

It's not unusual to be honest.
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gopher_49Author Commented:
I've seen these problems years ago with Symantec but with VIPRE I have so much disabled and configured to void issues...  I did see a bad URL option enabled for the server policy.  I turned it off and will now reinstall it.  I now know to simply remove if and when it happens again.  If it happens again I'll dig into it deeper.

Thanks.
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gopher_49Author Commented:
Shutting down the AV agent didn't fix it.  Like suggested..  It needs to be removed and added back... Once fully uninstalled my mail started to flow again.  I also have all Exchange folders disabled from scanning and no email scanning enabled, however, something still hung the SMTP process.  Uninstalling fixed it.  I then added it back.
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