need to change user properties in AD

You should be able to do this using a simple Set-User command with the ADSI extension. It would look something like this (assuming your headers in your CSV are MySamAccount,Mydescription):

$users = import-csv 'c:\setqadtestfile.csv'

foreach ($item in $users)
{
	$Id = $item.MySamAccount
	$desc = $item.Mydescription
	$usr = get-user $id
	$usrDN = $usr.DistinguishedName
	Set-User $id -Description $desc
	$AD = [ADSI]"LDAP://$usrDN"
	$AD."description" = $desc

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ack, lose the Set-User line. I did not mean to keep that in there.

Let's try that again:

$users = import-csv 'c:\setqadtestfile.csv'

foreach ($item in $users)
{
	$Id = $item.MySamAccount
	$desc = $item.Mydescription
	$usr = get-user $id
	$usrDN = $usr.DistinguishedName
	$AD = [ADSI]"LDAP://$usrDN"
	$AD."description" = $desc
	$Ad.SetInfo()
}

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If you are adding more than just the description attribute, make sure to use the attribute names as you see them in ADSI edit. For instance:
User Attribute Name                  ADSI attribute name
Title                                             title
StreetAddress                           streetAddress
Company                                   company
Office                                        physicalDeliveryOfficeName
Postalcode                                postalCode
City                                            l
StateOrProvince  `                    st
PhoneNumber                           telephoneNumber
Your header in your CSV would look like this:
MySamAccount,Mydescription,MyTitle,MyStreetAddress,MyCompany,MyOffice,MyPostalCode,MyCity,MyStateOrProvince,PhoneNumber

The code in the powershell script would looks as follows:

$users = import-csv 'c:\setqadtestfile.csv'

foreach ($item in $users)
{
	$Id = $item.MySamAccount
	$desc = $item.Mydescription
	$title = $item.MyTitle
	$address = $item.MyStreetAddress
	$company = $item.MyCompany
	$ofice = $item.MyOffice
	$zip = $item.MyPostalCode
	$city = $item.MyCity
	$state = $item.MyStateOrProvince
	$phone = $item.PhoneNumber
	$usr = get-user $id
	$usrDN = $usr.DistinguishedName
	$AD = [ADSI]"LDAP://$usrDN"
	$AD."description" = $desc
	$AD."title" = $title
	$AD."streetAddress" = $address
	$AD."company" = $company
	$AD."physicalDeliveryOfficeName" = $office
	$AD."postalCode" = $zip
	$AD."l" = $city
	$AD."st" = $state
	$AD."telephoneNumber" = $phone
	$Ad.SetInfo()
}

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Ok but am using cmdlets from quest  software in powergui can your script still work

Thank you so much it work fine