Exchange OWA client preview attachment

I have an Exchange 2007 SP2 install with all of our clients running OWA. I have 2 users that exhibit the following symptoms: After attaching a file to a new email, right clicking the attachment and selecting open result in the IE error message "Cannot display web page". Most of the other clients work and will open the attachment and I have 2 machines that are configured with the same XP SP3 / IE 8 and McAfee software, one works and the other does not using the same email account. I have reset the IE installation using the Advanced features with out success.
Clarity_IT_ManagerAsked:
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Clarity_IT_ManagerConnect With a Mentor Author Commented:
I think I found it but will have to do some more analysis. If I start IE without addons the problem resolves so I will try to disable them one by one to find what is causing the issue.
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naomelixesCommented:
Could the problem computer have some kind of adware/trojan/spyware, etc. messing up your IE?

I would try running Combofix (backup important data first) and then try again, it does fix weird browser errors, along with all the other cleanups it does.
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waleedaCommented:
please run run the Exchange Best Practice Analyser and see what is the issue
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naomelixesCommented:
I would really concentrate on the client machine(s), as the problem seems to be there...
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MegaNuk3Commented:
Try disabling/uninstalling mcafee on the faulty machine.

What happens if someone else uses OWA on the faulty machine, does the problem stay with the machine?

On another note, you should be on Exchange 2007 SP3 by now... ;-)
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Clarity_IT_ManagerAuthor Commented:
I will uninstall McAfee and try it again. The problem stays with the client regardless of the mailbox that OWA is used to connect with so it is definitely a client issue.
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Clarity_IT_ManagerAuthor Commented:
I removed McAfee and before reinstalling, I tried it again with no change. I am installing another antivirus package and will scan the machine before retesting.
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MegaNuk3Commented:
If you log into that PC as a new test user account, does the problem still exist?
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MegaNuk3Commented:
Ok
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Clarity_IT_ManagerAuthor Commented:
Root cause was determined but isolation in IE did not discover the problem. Refresh of the client to factory defaults may be the only resolution.
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