I have up-to-date versions of Firefox, Google Chrome and IE. When I click on a hyperlink, whether on a web page or in an email, nothing happens. Most of the time I can copy the link and paste it into another browser window, and it works--but not always. At first I thought it had to do with my mouse [which was starting to fail], but I've installed a new mouse that works in all other instances but not with hyperlinks.
Also, I can open a new window in Google Chrome and IE, but not in Firefox. Opening a new tab in any of these is not a problem.