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How to set autoreply for specific address on Exchange 2010

Dear experts,
Recently we upgraded our POP3 mail system to Exchange 2010.Every account on POP3 had a name of mailbox like John@domain.com and an alias like John.Smith@domain.com.
On Exchange 2010 I set mailbox account for John and added to E-mail Addresses of John's mailbox two addresses: John@domain.com and John.Smith@domain.com.Now every mail sent to both addresses arrive to the same mailbox.
My question is : how can I set auto reply so that everyone who send mail to John.Smith@domain.com will get the message from Exchange that this address will be deleted after X months ?Of course during this X months all incoming mails to John.Smith@domain.com should be delivered to the John mailbox. Mails sent to John@domain.com should be delivered without notification to sender.
2 Solutions
Muzafar MominCommented:
login using webmail and set out of office or use transport rule to set auto reply
You can create a rule using either Outlook, OWA, or Exchange Hub Transport Rules.  In Outlook you would Simply right click Rules on the ribbon bar and then say if a message was to John.Smith@domain.com, and then click next to select your action and put reply using a specific template.  You will need to create a template before doing this, but then you simply select it and everyone who emails John.Smith@domain.com will recieve the response, but not those who email John@domain.com

levkiperAuthor Commented:
Thanks.Can you explain how I configure Hub transport Rules.
I think it more preferable way since I need to set this rule for large number of accounts.
Praveen BalanSolution ArchitectCommented:
please follow this link for the transport rule, http://technet.microsoft.com/en-us/library/bb124737.aspx

Alternatively, rather easily you can create an additional mailbox with the email address  John.Smith@domain.com and enable an auto-forward (mailbox mail flow settings) to the mailbox John@domain.com. Set Auto Reply rule in John.Smith@domain.com mailbox.

Follow this for auto-reply
levkiperAuthor Commented:
Actually I didn't find auto reply option in Hub Transport rules.
It's a good idea to create additional mailbox for John.Smith with corresponding rule and deliver all incoming mails to John mailbox.
But I think ,the best solution is to create Outlook rule for John.Smith.Thanks Dustin99362.

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