large system files taking up to much space

In the system volume information of my NON-OS drive I've got system files taking up 53 gig on a 300 gig partition. Shadow copies are completely disabled. What can be done, and is this normal?
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Are you dual booting, mounting the drive with an application, or none of the above?
tfgeorgeAuthor Commented:
ThorinO: none of the above. It's an exchange server with the DB on it.
tfgeorgeAuthor Commented:
Even with shadow copies disabled, shadow copies can be working to take up space. They needed to be deleted.

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tfgeorgeAuthor Commented:
no one answered the question so I had to accept my own.
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Windows Server 2008

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