Is the XP local profile related to the USB port configuration? No power is going to the USB optical mouse.
This is a Dell Latitude D600 running Windows XP Pro SP3. Dell Diagnostics tests the USB ports and reports everything is OK.
I used Microsoft Device Manager to delete the 4 USB hubs and restarted the computer. All 4 USB hubs were recreated after the reboot.
I have 3 different user accounts on Windows XP. All 3 reported "cannot load local profile", when I logged into them.
All USB devices are dead. This includes keyboard, mouse, and flash drive.