Problems with sending mail Exchange 2010?

Here is what I have:
When trying to send mail from Outlook Web App the message just sits in queue and give me this error:
451 4.4.0 primary target IP address responded with "421.4.4.2 unable to connect."attempted failover to alternate host, but that did not succeed.Either there are no alternate hosts, or delivery failed to all alternate hosts.

I am running Exchange 2010 on Server 2008 R2. My internet provider is uverse. I use the residential gateway as a modem and use a Linksys E2000 for my router. All mail ports are open and I can telnet my mail server on port 25.

Any help would be appreciated.

Thanks,
Tony
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askurat1Asked:
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askurat1Connect With a Mentor Author Commented:
I created a DynDns account and used it as smarthost to send email.
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wdurrettCommented:
Hi.

Have you checked to see if thsi is for all domains or just some domains?  Can you send mail form Outlook?
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wdurrettCommented:
This may be a fix for you given your setup.

http://support.microsoft.com/kb/951291

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askurat1Author Commented:
I have just set this up and just trying to send a test email. I have not tried it in outlook and I have tried sending to 3 different domains.
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askurat1Author Commented:
I am trying the link now.
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askurat1Author Commented:
Didn't work.
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wdurrettCommented:
Hi Askurat1.

Did you try sending to other domains?  Send me an email: wes AT kzoons.com

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askurat1Author Commented:
I've tried that with 3 other domains and also tried sending one to you. Still same error.
I also get this in my Send log:
2011-04-26T17:12:32.654Z,Internet Send Connector,08CDD23C2B3B9E67,1,,66.128.105.120:25,*,,"Failed to connect. Error Code: 10060, Error Message: A connection attempt failed because the connected party did not properly respond after a period of time, or established connection failed because connected host has failed to respond 66.128.105.120:25"

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askurat1Author Commented:
I have figured out I can send mail to any of my users but not to any external domains.
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wdurrettCommented:
Look under

Organization Configuration> Hub Transport> Send Connectors

and make sure you have it configured correctly.
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askurat1Author Commented:
I have and everything seems to be configured correctly. Anything I should go off of?
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askurat1Author Commented:
Also found out the uverse blocks port 25.
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askurat1Author Commented:
Found my own solution.
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