Here is what I have:
When trying to send mail from Outlook Web App the message just sits in queue and give me this error:
451 4.4.0 primary target IP address responded with "4188.8.131.52 unable to connect."attempted failover to alternate host, but that did not succeed.Either there are no alternate hosts, or delivery failed to all alternate hosts.
I am running Exchange 2010 on Server 2008 R2. My internet provider is uverse. I use the residential gateway as a modem and use a Linksys E2000 for my router. All mail ports are open and I can telnet my mail server on port 25.
Any help would be appreciated.