Have a user who has Acrobat Reader X loaded on her laptop. Her system is a Dell Laptop, XP SP3, Office 2003, fully up to date and she is a local admin. When she tries to open Acrobat, she receives an error message "Sorry Acrobat has encountered an error and needs to close".
I followed the advice in the article below about doing a run-as administrator and disabling projected mode:
This got Acrobat open when running under the local administrator account, but when I disable projected mode in the settings there, it appears to only affect the account Acrobat is running under (admin), as when I try to run it as the logged in user, I still receive the same error message.
Seems as though if I had a way to disable protected mode for all users that it would resolve the problem. I did some searching but didn't come up with anything. I found a release from Adobe on 4/28 stating that the new patch will address a lot of these issues, but of course, telling someone to wait for a patch isn't really a solution since they effectively cannot work if they are unable to open PDFs.
I also tried doing both a repair and an uninstall/reinstall, but the problem persists.