Slow running computer

My computer is running very slow.  It has Windows XP Home, an AMD Athlon 64 3400+, 2 gig memory, and less than 20% of my hard drive has been used.  I went ahead and downloaded SuperAntiSpyware and quarantined some items.  I then did HijackThis and attached the file but I'm not sure what I should remove?
William RichardsonAsked:
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akahanConnect With a Mentor Commented:
It appears you've been infected.  I would run malwarebytes, doing a full (thorough) scan.  And uninstall all those stupid toolbar helpers, they're not helping you:

R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyServer = http=

O2 - BHO: My Search BHO - {014DA6C1-189F-421a-88CD-07CFE51CFF10} - C:\Program Files\MySearch\bar\1.bin\S4BAR.DLL

O3 - Toolbar: My Search Bar - {014DA6C9-189F-421a-88CD-07CFE51CFF10} - C:\Program Files\MySearch\bar\1.bin\S4BAR.DLL

O3 - Toolbar: Nero Toolbar - {D4027C7F-154A-4066-A1AD-4243D8127440} - C:\Program Files\\GenericAskToolbar.dll

Can you go into Control Panel/Add Remove programs, and remove these toolbars (My Search, Ask, etc.)?

It certainly looks like an infection.  When you run Malwarebytes(as suggested), download and update it from here:

Ensure you run in normal mode.
When installation has finished, leave both of these checked:
Update Malwarebytes' Anti-Malware.
Launch Malwarebytes' Anti-Malware.
Click Finish, and MBAM will automatically start.

Tutorial, if required:

Then try Hitman Pro, a second opinion scanner:
Hitman Pro

Also Dr.Web CureIt!®

and ...
ESET Online Scanner, another free, & powerful tool: 

That may well do the trick, but please report back on progress.
Here's an excellent article to follow, written by E_E's younghv >>
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