SMB Performance Enhancements / WIndows Server 2003

I am looking into any and all ways to speed up file transfer using SMB, over a VPN. Data is being copied back and forth via SMB between a Windows Server 2003 and a Cisco NAS device.
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Felix LevenSenior System and DatabaseadministratorCommented:
Good Point to start is the "Performance Tuning Guidelines for Windows Server 2003" on Page 23:

All Info about SMB and important Reg-Keys you can change. Think about upgrading to 2008 R2 on the long run, SMB really improved.
The only thing I can recomend would be to beef up what ever type of connection between point A & point B for your VPN. Inside your LAN there are a few things you could try such as making sure the NICs & the switch ports are set to 100/full duplex.
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