Warning when adding Enterprise Keywords to Content Type

In SharePoint 2010, I received the following warning when attempting to add the Enterprise Keywords column to a custom Content Type. I need more information than this - what clients will be impacted, and how?

The site column 'Enterprise Keywords' might not be supported by earlier versions of client programs. Adding this column might block those programs from saving documents to this library. Are you sure you want to use this site column?
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As far as I can find they are supported within Office 2010. If the end-user is using an older version of Office he can't save the document from within word when the field is required. The field is also not editable from the datasheet view.
jessc7Author Commented:
Thanks - Here's a little more information as well, across Office 2003 and 2007
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