Junk mail Exchange 2010

Mayogroup
Mayogroup used Ask the Experts™
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One of our internal systems generates emails to our users. The mail seems to appear in the junk mail of majority of the users (those who haven't created a personal junk mail rule).
Is there anyway to set a rule from exchange which will apply to all?
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a little more information would be good ... but I am making some assumptions.

Try safelist aggregation in Exchange 2010.  Quoted from MS, "Safelist aggregation can help reduce the instances of false-positives in anti-spam filtering performed by the Edge Transport server. A false-positive is a positive test or filter result in a subject or body of data that doesn't possess the attribute for which the filter or test is being conducted. In the context of spam filtering, a false-positive occurs when a spam filter incorrectly identifies a message from a legitimate sender as spam."

link on how to do it : http://technet.microsoft.com/en-us/library/bb125168.aspx

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Commented:
We aren't using Edge Transport Service.
What other informating do you need?
use EMS:

Set-ContentFilterConfig -BypassedSenders foo@somedomain.com

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