Paperport 12.1 failure to send a scaned document to Outlook 2010

Have used PP 11, PP 12 Pro and then PP 12.1 Pro. I have always been able to scan a document on my Brother MFC-7420, seen it go to the PP desktop, where I could highlight the document and then send it to Outlook to be e-mailed. All of a sudden I started receiving the following eror message,"Either there is no default mail client or the current mail client cannot fulfill the requested message. Please run Microsoft Outlook and set it as the defauly mail client." Outlook is my default mail client, I have downloaded PP 12.1 which was supposed to fix the problem, I have uninsatlled and reinstalled the PP software, etc., etc. I can save the scans in a folder and then attach the saved document to an e-mail. Also if none of the scans on the PP desk top are highlighted, I can click on the Outlook icon and Outlook will appear, so the desktop can comunicate with Outlook, but I can't send a scan to Outlook.Nuance has not been of any real help. Does anyone know how to fix this problem?
Thank you, Verdi1818