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Can't access flashdrive

When I insert my flashdrive into an SLC400c it recognizes that new hardware has been found. When I go to My Computer and double click on the folder for the flash drive (which has been found) nothing opens. When I try to Safely Remove Flash Drive I get the message that it cannot remove the device - "The device Generic volume cannot be stopped right now".
When I put the same flashdrive in a different laptop it recognizes the drive and I can open and access the files. However, it does run some sort of virus scan when inserted into this other laptop. I feel that when I put it into the SL400c it is running some sort of program in the background which is preventing me from accessing the drive. We had erased some ini files that were deeply hidden and the problem seemed to be resolved for a day. But now we are back to the same problem. I even copied the files to a different flashdrive and had the same problem.
Any thoughts or ideas would be greatly appreciated.
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Thanks for the response. It triggered some thoughts in me to try to disable the autoplay. I was able to go into GPEDIT and enabled "Turn off autoplay". I can now use the flash drive.

Thanks again..
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