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Even if malware is sparse, is there any recommended ant-malware apps for Mac OSX?

Hi Mac Experts, we have more Macs showing up in our work environment now days.  In the Windows world there are already a well known list of favorites for anti-malware (MSE, Super Anti-Spyware, MBAM, etc).  Although the mac is considered to be relatively malware free, is there anything good and reliable out there that can be used for periodic scans just to be safe or make funders happy (non-profit environment)?  

The macs are used for important information just like the Windows machines now days (online banking, client data, etc) so we want to make sure the "malware free" reputation doesn't cause users to go crazy.  Unfortunately, the users do know (and we can' avoid this for misc reasons) their admin password and of course can be easily tricked into typing it for malware like the recent macdefender malware, etc.

Or . . . . is it truly not a problem even if you use your Macs for more than just web surfing?

Thanks
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Thanks.  Is it easy enough to evaluate these products and remove them in MAC OSX?  In Windows it's sometimes a pain to get rid of an old anti-virus and you end up running apps like the Norton removal tool, etc.  

Would like to try clamav and compare to others, but don't want to clutter up OSX either (especially since Lion requires a clean install from the web apparently and we don't have any imaging solutions in place for macs yet).

Thx
I think the clamXav comes with an uninstaller which will remove everything.

Sometimes just dragging the app to the recycle bin is enough, but sometimes little bits get left behind. There are apps that will help remove these bits.

Try http://www.macupdate.com/info.php/id/10051
mac are susceptible to trojans which can easily be installed even though you have virus protection. Make sure that you users are educated not to get tricked into installing trojans on their machine. This is 10 times more important than the virus software as of this writing.
If you don't use software from untrusted sources (pirated applications) you don't need to use an antivirus solution on OSX. It will only slow down your systems.
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Thanks service.  What about web browsing and what not?  Are there similar browser exploits on Safari/MAC as their are on Windows?
Web exploits are not the main concern. The biggest concerns are trojans in that people can be tricked into installing malicious software. Rougeware would fit into that category as well. Self spreading and self-replicating code seem to be nearly non-existent on the Mac.
Picking up on the thoughts of others about trojans, I've checked the Kaspersky website and it says the Internet security product detects viruses, worms, trojans, and bots.
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Out of curiosity, those of you that run AV or security suites, has it ever found anything on your MAC?
No...not yet anyway!
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Thanks, anyone else?
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mccrick - The trojans you mention, are these things that would be detected from solutions like ClamXAV?  If not, how can our mac machines be checked for them?  Is there a procedure or anything we can do to check?

Thanks
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Thanks.  Agreed informing users is the best way to go.  The question is, while in the process of doing that, what's a good reputable way to check Mac OSX when it's been used by users who are "still learning."  
Seriously: Mac OS X versions (10.0-10.7)

If you want more you can run ClamXAV. This is a nice way to help ensure that you are not spreading PC viruses to PC users.

http://www.clamxav.com/
Jsmply:
mccrick - The trojans you mention, are these things that would be detected from solutions like ClamXAV?  If not, how can our mac machines be checked for them?  Is there a procedure or anything we can do to check?

Based on the behavior of PC based Virus protection, I would have to assume that it would catch some and not others. But without the occasional virus or malware to battle, it's hard to test.

Similar to trojans is Rougeware. Educate your users about this. It may be the biggest threat to Mac users:
http://printceo.com/2011/05/new-mac-rogueware-alert/
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mccrick - You said "Seriously: Mac OS X versions (10.0-10.7) "

What did you mean by that?
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Thx all, will give clamxav a try.