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Exchange Server 2010 sp1 can not send email via hosted with local program to other smtp servers

First of all, in the local exchange accounts can sends email to everywhere.(LAN or outside)
But a written software which hosted in local area network, can send emails to exchange servers accounts, but it can not send emails outside.
Is there a configuration about it, because I really don't think that written software has a connection problem with the exchange server.
ExchangeEmail ProtocolsDNS

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8/22/2022 - Mon

how you configured the authentication in that software?
Did you create that sender account in exchange?

Why are you using the Program to send emails, is it for bulk mailing?

If yes, you better look for Bulk E-Mail Providers .. Otherwise, your Server might be blacklisted by Spam Checkers or hence blocked by many Mail Servers.

Anyways, if you are using SMTP , make sure your Exchange is accepting/relaying SMTP connections from the Server which you installed your Application.

A web application which is hosted in my local area network must send some auto emails to somewhere. Normally with outlook everyone can send emails and there is no problem, but when the web application wants to send emails to outside, emails can send to exchange server accounts but can not send to outside (other smtp).
If our server might be blacklisted by spam checkers, we could not send emails to outside with outlook. Bu we can send emails with outlook web access. The problem is the web application connects to exchange server with c# code, then while written emails can send to exchange server accounts, but can not send outside(to other smtps)
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William Peck

Basically you want to act your  Exchange Server as a relay.

Follow this excellent link,


Basically, allready have sender account in exchange created, and account parameters written in codes of program, and program send reply mails via exchange server to persons who has account in the exchange server. Problem is  application cannot send reply mails (for forgotten password replies of the application) to external e-mail accounts, Whereas this e-mail account which is created sender account can send e-mail everywhere via outlook web app.

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