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URGENT - SBS 2008 not sending and receiving email

I have a SBS 2008 with exchange 2007 not sending email

This is the error I see in the queue
451 4.4.0 primary target ip address responded with 421 4.2.1 unable to connect

After I did a test I see that he and all other users are not receiving any emails either.
The email that the users are trying to send are all in the queue with the error above

I has this same problem a few weeks ago on the server and rebooted the server which solved the problem. Today I have already rebooted twice and no luck.
This is the post from a few weeks ago
http://www.experts-exchange.com/OS/Microsoft_Operating_Systems/Server/SBS_Small_Business_Server/Q_27247029.html

Please help.
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Gerhardpet
Asked:
Gerhardpet
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1 Solution
 
5g6tdcv4Commented:
are all exchange services running on the server?
Does BPA report any errors?
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5g6tdcv4Commented:
is the database mounted...?
any event log errors regarding exchange?
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GerhardpetAuthor Commented:
Yes exchange is running. What is BPA and where to I check for errors?
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5g6tdcv4Commented:
Best practices analyzer
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GerhardpetAuthor Commented:
I don't see anything obvious in Best practices analyzer

Below is the scan I did and perhaps you can look at it


All Issues  
  Windows SBS Update Services not at default setting :  
 Synchronization Options for Windows Server Update Services is not set to All Microsoft Products. Because of this, software updates are not managed by Windows SBS 2008 Update Services. This results in a blue question mark in the Updates section of the Windows SBS Console. For more information, see the Microsoft Web site (http://go.microsoft.com/fwlink/?LinkId=103721).
 
  Windows SBS Update Services not at default setting :  
 Windows Server Update Services is not set to store files locally. The Store Update Files Locally option is not selected in the Update Files and Languages properties for Windows Server Update Services. Because of this, software updates are not managed by Windows SBS 2008 Update Services. This results in a blue question mark in the Updates section of the Windows SBS Console. For more information, see the Windows SBS 2008 Technical Library at the Microsoft Web site (http://go.microsoft.com/fwlink/?LinkId=103721).
 
  Windows SBS Update Services not set to default settings :  
 Server Targeting for Windows Server Update Services is not selected. The Server Targeting option is not selected in the Computers properties for Windows Server Update Services. Because of this, software updates are not managed by Windows SBS 2008 Update Services. This results in a blue question mark in the Updates section of the Windows SBS Console. For more information, see the Windows SBS 2008 Technical Library at the Microsoft Web site (http://go.microsoft.com/fwlink/?LinkId=103721).
 
  Local activation permission to the IIS WAMREG Admin Service required :  
 The Network Service is missing local activation permissions to the IIS WAMREG admin Service in accordance with the event ID 10016 in the system event log. For more information, see KB "Event ID error messages 10016 and 10017 are logged in the System log after you install Windows SharePoint Services 3.0" at http://go.microsoft.com/fwlink/?LinkId=128063. Note: This warning will continue to appear until at least 24 hours have passed since the most recent occurrence of event 10016.
 
  The BackConnectionHostNames registry key does not exist :  
 The registry key HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Lsa\MSV1_0\BackConnectionHostNames does not exist. To resolve this issue, open Registry Editor, and then locate and click HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Lsa\MSV1_0\. Right-click MSV1_0, point to New, and then click Multi-String Value. Type BackConnectionHostNames, and then press ENTER. Right-click the BackConnectionHostNames key, and then click Modify. In the Value data box, add the names "companyweb" and "remote.kargomax.ca" (do not include the quotation marks), and then click OK. Exit Registry Editor and then restart the IISAdmin service. For more information see the Knowledge Base article "Errors when crawling content sources in SharePoint Server 2007: "Event ID 2436" and "Access is denied"" at http://go.microsoft.com/fwlink/?LinkId=195553.
 
  The DNS parameter MaxCacheTTL is not set :  
 The DNS parameter MaxCacheTTL is not set. For more information, see "Windows Server 2008 DNS Servers may fail to resolve queries for some top-level domains" in the Microsoft Knowledge Base at http://go.microsoft.com/fwlink/?LinkId=152402.
 
  The log file for the Windows SharePoint Services configuration database is getting large :  
 The log file for the Windows SharePoint Services configuration database is larger than 1 GB in size. For information about how to reduce the size of the log file, see the Knowledge Base at http://go.microsoft.com/fwlink/?LinkId=159745.
 
  User account does not show in the Windows SBS Console :  
 The user account MWService does not have the attributes that are necessary for it to display in the Windows SBS Console.
 
  User account does not show in the Windows SBS Console :  
 The user account trend admin does not have the attributes that are necessary for it to display in the Windows SBS Console.
 
  User account does not show in the Windows SBS Console :  
 The user account Printer does not have the attributes that are necessary for it to display in the Windows SBS Console.
 
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GerhardpetAuthor Commented:
Finally found out that the ISP blocked port 25 without letting me know
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GerhardpetAuthor Commented:
Found the problem myself
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