Windows Server 2008 and Windows Server 2008 R2, based on the Microsoft Vista codebase, is the last 32-bit server operating system released by Microsoft. It has a number of versions, including including Foundation, Standard, Enterprise, Datacenter, Web, HPC Server, Itanium and Storage; new features included server core installation and Hyper-V.
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There is a validation wizard in the cluster management console: it could help you pinpoint potential issues before implementing your cluster.
The following document could provide you with further information regarding the iSCSI implementation:
http://www.google.com/url?sa=t&source=web&cd=2&ved=0CCIQFjAB&url=http%3A%2F%2Fdownload.microsoft.com%2Fdownload%2Fa%2Fe%2F9%2Fae91dea1-66d9-417c-ade4-92d824b871af%2Fuguide.doc&ei=PlZnTt7kB4q28QPvrbz5Cw&usg=AFQjCNFr53hAJBhIWjVhxjJ1JB31zUb97w