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How to route email traffic from Front-End Exchange server to failover Back-End Exchange Sever

I have a front-end email server in the DMZ and it communicates with a back-end email server in the INSIDE network.  Everything is working fine.  My question is what tells the FE server what BE Exchange server to use?  I don't remember ever telling the FE that here is the BE server...It just found it (probably by saying "this is a back-end" or this is a front-end" in the RPC-HTTP properties of the server).  But what happens if I need to fail over to a backup Exchange server?  How does the FE know to redirect the email traffic to the failover Exchange server and not he primary Exchang server that is down?  Thanks in advance!
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That would make sense.  So if I have failed over to the failover server, do I need to reboot the FE server for it to start talking to the failover server where the database is mounted or does that happen automatically?
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Failover Exchange Server using something called Double-Take that mirrors the Exchange info to another server.  In testing, the failover server is working (users are connecting to it) but the FE doesn't seem to be working (I know there's a lot that goes into that - firewall commands, etc.) and iPhones/iPads aren't connecting.  And the more I thought about it, the more I wondered how the FE knows where the BE is if you have two BE's (one primary, one backup).
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Yep, had to install RPC over HTTP on failover server (it wasn't there) and then reboot.  Started working then so it's all tied into AD.  Thanks!