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See if Enable Protected View for Outlook attachments is checked and uncheck it if so.
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See if Enable Protected View for Outlook attachments is checked and uncheck it if so.

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I have ONE user that can't open word/excel/ 2010 attachments from Outlook 2010.<br />
<br />
I have removed and reinstalled Office 2010 and have run the 2003 Outlook fixit tool and the 2010 fixit tool. <br />
<br />
Thanks.
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I have ONE user that can't open word/excel/ 2010 attachments from Outlook 2010.

I have removed and reinstalled Office 2010 and have run the 2003 Outlook fixit tool and the 2010 fixit tool. 

Thanks.

Can't Open .docx attachment from Outlook 2010

Microsoft Outlook is a personal information manager from Microsoft, available as a part of the Microsoft Office suite. Although often used mainly as an email application, it also includes a calendar, task manager, contact manager, note-taker, journal, and web browser.