I have a similar problem kind of....
We have Backup Exec 2010 and a HPDAT160 USB tape drive.
When we enable the compression on the drive with HP Tapetools the drive is ok.
But as we start Backup Exec 2010 the value by device manager go's from enabled to disabled and the job Wil stick at 80 GB Of data.
OS: Windows SBS 2011
Can anyone help?