Ever since I upgraded to Adobe Reader X (not 10.1.1) I have had problems with the application freezing. I see many references to this on various forums, but no solid solution. I've used earlier editions of the Reader for 15+ years without a problem.
The application freezes:
100% of the time when I choose a document form the application splash screen.
Intermittently when I choose a document from the file/open menu choice, usually on the 2nd or 3rd document.
The freeze blocks leaving the app; I have to re-boot the computer - a real joy when trying to to a "quick" document retrieval.
PS - Sorry for the Zone pick, but I couldn't find Adobe Reader