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Is the RPC service running on the DC?
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Yes the RPC service is up and running on the DC's, and the corresponding service on the exchange server also shows as started, and wont let me restart or stop it without rebooting the server. 
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Yes the RPC service is up and running on the DC's, and the corresponding service on the exchange server also shows as started, and wont let me restart or stop it without rebooting the server.

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Are you using the original admin credentials? (used to install the OS)
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Are you using the original admin credentials? (used to install the OS)

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When logging onto the server? were using a domain admin account, all the services run under the original credentials though yes. 
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When logging onto the server? were using a domain admin account, all the services run under the original credentials though yes.

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<div class="content wysiwyg-content">
We are running Exchange Server 2003, for the last couple weeks every few days we will have several people complain that they cant connect to their E-mail.<br />
<br />
When We remote into the Exchange server we get a message stating “The system cannot log you on due to the following error: The RPC server is unavailable” when trying to login to the network. Logging into it using the local admin account works fine though.<br />
<br />
The only way we've been able to get everyone to reconnect properly is to reboot the server.<br />
<br />
When checking the Event Logs there is no error/warning messages that seem to indicate what might be causing this. <br />
<br />
Thanks<br />

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We are running Exchange Server 2003, for the last couple weeks every few days we will have several people complain that they cant connect to their E-mail.

When We remote into the Exchange server we get a message stating “The system cannot log you on due to the following error: The RPC server is unavailable” when trying to login to the network. Logging into it using the local admin account works fine though.

The only way we've been able to get everyone to reconnect properly is to reboot the server.

When checking the Event Logs there is no error/warning messages that seem to indicate what might be causing this. 

Thanks


Keep having to reboot Exchange server due to Message &quot;There is no RPC Server available&quot;

Microsoft applications include a variety of software programs, including development and digital authoring programs (Expression and Media Center), educational programs, Internet software, including Essentials, Skype and the Live family, anti-virus, productivity applications and suites like Office, Excel, Word, Outlook, Access and PowerPoint, video games and server applications such as Exchange, SharePoint, IIS and Virtual Server.

Microsoft Applications

Microsoft Outlook is a personal information manager from Microsoft, available as a part of the Microsoft Office suite. Although often used mainly as an email application, it also includes a calendar, task manager, contact manager, note-taker, journal, and web browser.

Outlook

Within Internet message handling services (MHS), a message transfer agent or mail transfer agent (MTA) or mail relay is software that transfers electronic mail messages from one computer to another using a client–server application architecture. A MTA implements both the client (sending) and server (receiving) portions of the Simple Mail Transfer Protocol (SMTP). The terms mail server, mail exchanger, and MX host may also refer to a computer performing the MTA function. The Domain Name System (DNS) associates a mail server to a domain with mail exchanger (MX) resource records containing the domain name of a host providing MTA services.

Keep having to reboot Exchange server due to Message &quot;There is no RPC Server available&quot;

Keep having to reboot Exchange server due to Message "There is no RPC Server available"