Group membership caching server 2008 ent x32 domain

On my site I have about 3 DCs (all global catalogs) and site2 has 2 DCs (all global catalogs).  Should I enable 'Group membership caching on all DCs on all sites?
Help plz
amanzoorNetwork infrastructure AdminAsked:
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GovvyConnect With a Mentor Commented:
The setting would take no effect if enabled since all your DC's are already GC's.
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