Exchange 2003 can't send to 1 domain from 1 user

I have 1 user who cannot send to 1 domain we get this message on the return:

      '' on 10/3/2011 9:10 AM
            You do not have permission to send to this recipient.  For assistance, contact your system administrator.
            < #5.7.1 smtp;550 5.7.1 Sender ID (PRA) Domain Does Not Exist>

It will fail from any pc that we use and everyone else can send to this domain.  
I am lost
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AmitIT ArchitectCommented:
It seems, user is sending to a DL, which might be restricted to accept message for specific people. You might need to ask other domain admin to allow this user also to relay the email to this DL.
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