Why are our SharePoint sites are preventing user access sporatically?

Myself included, who is a farm admin, has run into this issue. I am able to edit list settings, entries, sites, etc. most of the time. Then from time to time I will be basically locked out and have no access to edit anything for a minute or two, then my access returns. Has anyone else experienced something similar? I am curious if the Web Page Security Validation has anything to do with the issue.
Thank you
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dserotkoAuthor Commented:
I am curious if anyone knows of an issue with Windows Integrated Authentication and SharePoint?
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dserotkoAuthor Commented:
Better pic:
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dserotkoAuthor Commented:
This ended up being an external backup that was running hourly. It made everything read only while it ran.

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