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Windows Server 2008 and Windows Server 2008 R2, based on the Microsoft Vista codebase, is the last 32-bit server operating system released by Microsoft. It has a number of versions, including including Foundation, Standard, Enterprise, Datacenter, Web, HPC Server, Itanium and Storage; new features included server core installation and Hyper-V.
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Not sure why you would need to delete any files on the client. Sometimes we run into profile issues where we need to delete a corrupted profile on the server or workstation to have it re-sync one way or the other. The only issue might be is if you need to reorganize or move any of the profile to another directory. You may need to coordinate a reboot on the workstations, because they will not get the updated profile path location until a reboot. Hope this helps.