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May I ask what you're Proxy is?<br />
<br />
some Proxy can force the IE to have a default configuration like ISA.
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May I ask what you're Proxy is?

some Proxy can force the IE to have a default configuration like ISA.

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also Domain Policy. you might check it as well.
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also Domain Policy. you might check it as well.

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is a ISA server, how i get rid of that default configuration?
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is a ISA server, how i get rid of that default configuration?

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in explorer in connections, then lan settings the &nbsp;local area network setting &nbsp;the automatically dectect settings, in the automatic configuration check mark is always selected even when I deselected, sometimes it comes again immediately and sometimes it will come in a day or so, but always the check mark will come back.<br />
The are in a network and all the machines have the same symptom.<br />
I use a proxy server for lan. 
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in explorer in connections, then lan settings the  local area network setting  the automatically dectect settings, in the automatic configuration check mark is always selected even when I deselected, sometimes it comes again immediately and sometimes it will come in a day or so, but always the check mark will come back.
The are in a network and all the machines have the same symptom.
I use a proxy server for lan. 

in explorer in my local area network setting  the automatically dectect settings, checkmark is always seleted?

The Windows operating systems have distinct methodologies for designing and implementing networks, and have specific systems to accomplish various networking processes, such as Exchange for email, Sharepoint for shared files and programs, and IIS for delivery of web pages. Microsoft also produces server technologies for networked database use, security and virtualization.

Windows Networking

Web browsers are applications used primarily to display documents, files and media from the Internet, identified by a Uniform Resource Identifier (URI) that can be a page, image, video or other file. Some browsers require the use of add-ons or extensions to safely render the information they receive; others have systems built into them to perform the same functions.

Web Browsers

Servers are computing devices that are similar to desktop computers in that they have the same basic components, but are significantly different in size, configuration and purpose. Servers are usually accessed over a network, and many run unattended, without a computer monitor, input device, audio hardware or USB interfaces. Many servers do not have a graphical user interface (GUI), and are configured and managed remotely. Servers typically include hardware redundancy such as dual power supplies, RAID disk systems, and ECC memory, along with extensive pre-boot memory testing and verification. Critical components might be hot swappable, and to guard against overheating, servers might have more powerful fans or use water cooling.