After using the search feature, I seem to be coming up short so I appologize if you've seen this before. I'm currently logged in as the local admin in safemode and cannot run HiHackThis or Malwarebytes after using Kaspersky's TDSSKiller to remove several rootkits as recommended as a solution for search engine results that are being redirected. But now that the machine has rebooted, I'm told "Windows cannot access the specified device, path, or file. You may not have the appropiate permissions to access the item."
I've checked NTFS permissions for the related folders with no indication of a problem. One odd thing is that I can't even rename the Malwarebytes or HiJackThis files. Whatever this is, it seems to know I'm trying to kill it. Seems malware just keeps getting worse and finds its way in regardless of the anti-malware and anti-virus package you choose.