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Resource shortcuts are currently disabled.  how to "enable" citrix xen app?

puzzledten-fold
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Last Modified: 2012-06-21
1.     i used RegWork to clean up my registry this AM.
2.     since then,  i've been unable to access certain applications at a secure website that my medical center uses.
3.      i've removed and reloaded software for the two websites (cleveland clinic intranet 4corners and citrix app and plug-in.
4.      using citrix, i i can get to the cleveland clinic website and enter my ID and password;
5.      i then go to a second cleveland clinic website that has published apps and published bookmarks;  i can get into the bookmarks, but not the apps.  when i try to open the apps by opening a new tab, it takes me to the following URL:  http://wi.ccf.org/RA/4Corners/site/default.aspx?CTX_MessageType=WARNING&CTX_MessageKey=ShortcutDisabled  
6.       the error message is the title above.  
7.      did cleaning the registry do something such that now citrix published apps are disabled?
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