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RPC over HTTP Not Working

I am having some major configuration issues in my new exchange 2010 environment.  I have exchange 2010 fresh install with majority of clients on office pro plus 2007.  I had a problem with them getting prompted for username and password.  I finally fixed that by getting the correct ssl cert for autodiscovery.  Now that that id fixed I am having a problem of RPC over HTTP not working.  When my users are in the office (Outlook 2007 or 2010) they connect up fine.  ONce they leave the office all they get is Trying to connect in the bottom right corner.  Will not connect up when you test connection from outlook icon.  Autodiscovery is working though.  I do not know what to do.

It also works just fine on the smartphones.

Any ideas??????
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Getsum_Bloodlust
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Pavel Nagaev
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Of course https://www.testexchangeconnectivity.com/. I made mistake in previous post and unable to edit it. Sorry.
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I appreciate everyones help.  I ended up just rebooting the server and everything started working.  I am not sure if the restarting of IIS or the services fixed it but it is working again.  Once again thank you all for your help.