Email Server failure

Please help.  About three years ago we had installed a new Windows 2008 server with exchange 2007 installed on it.  Now on the network this server acts as the exchange server and the  Domain Controller.  About one week ago there was a hard drive failure which caused Dell to come on out and replace it.  The drives were on a RAID 5 config so that should not have been a problem for them.  About 4 or 5 days after that every single morning we are waking up to the server not working.  And when I would log on there would be a ton of error messages from Microsoft MMC and now more recently Windows explorer. And I would have to reboot the entire Server just to get everything back. What the heck is going on ?!?!  Please help.
FrankieD1125Asked:
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NetfloCommented:
Run a CHKDSK on your OS drive, first in read only mode. You seem to have some problems with the disk integrity which will need to be fixed with CHKDSK. Ensure you have a full server backup before proceeding with anything though, VERY IMPORTANT!

I would also check that all your drives in your array are on the latest firmware and same size disk cache. I've seen a scenario where the cache size of a replacement drive was causing the RAID array to flip out and cause the server to go offline.

I would get Dell to doublecheck your setup and explain that you have concerns on server stability since replacing a drive. I would not allow them to fob you off, clearly there is an issue.

If its a subsystem issue, that needs to be addressed first from Dell!

Hope this helps.
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FrankieD1125Author Commented:
THESE ARE SOME OF THE ERROR MESSAGES THAT COME UP ON THE EVENT LOG JUST BEFORE STORE.EXE TERMINATES UNEXPECTANTLY.

Resource-Exhaustion-Detector
Windows successfully diagnosed a low virtual memory condition. The following programs consumed the most virtual memory: store.exe (6972) consumed 1411899392 bytes, w3wp.exe (4832) consumed 349605888 bytes, and EdgeTransport.exe (5380) consumed 274378752 bytes.


And..

Voltage sensor returned to a normal value
Sensor location: PS 1 Voltage 1
Chassis location: Main System Chassis
Previous state was: Unknown
Voltage sensor value (in Volts): 122.000

And...

An I/O operation initiated by the Registry failed unrecoverably.The Registry could not flush hive (file): '\SystemRoot\System32\Config\SOFTWARE'.    EVENT ID - 6
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NetfloCommented:
Slightly off topic question, is your server up to date in terms of OS service pack (SP2) and Exchange service pack (SP3)?

How much RAM do you have in this server and approx how  many users have mailboxes on this server?
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FrankieD1125Author Commented:
Yes,  Every update has been performed and the server has 8GB of RAM with just under 50 users.
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NetfloCommented:
Then do you want to perform a CHKDSK in read only mode, it can be run safely during operational hours with no downtime. Based on the results of that, you will know if you have to fix that or not. Should take no more than 20 minutes to run.
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andyalderSaggar maker's framemakerCommented:
You have the w3wp.exe hotfix installed?
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NetfloCommented:
Andyalder, do you mind posting a link to this hotfix? Thanks
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NetfloCommented:
FrankieD1125 or andyalder, any update?
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