I need a quick way to force users to go through Outlook setup

Exchange 2010

Is there a flag somewhere or something that will force the user to run setup and autodetect their email account the next time they run Outlook client?  We have just completed and upgrade and client machines/profiles are still trying to reach the old server/domain.  We can repoint manually but have many users.  help.
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Maen Abu-TabanjehNetwork Administrator, Network ConsultantCommented:
is autodiscover enabled? please run this command on powershell :

get-autodiscovervirtualdirectory |fl
get-clientAccessServer |fl
get-webservicevirtualdirectory |fl
get-outlookanywhere |fl

and post results here , to detect the problem you have.

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