I am using a Logitech MediaPlay wireless mouse with the latest version of Logitech software (SetPoint 6.32.7). The problem is that in Windows 7 I cannot permanently switch the function of the left and right buttons (make it left-handed). SetPoint doesn't claim to be able to do this, but with previous versions of Windows I have been able to do it in the Control Panel with a check box that says "Switch primary and secondary buttons." The check box is still there, and it still works ... until the next reboot. I called the Logitech help desk and this was the best they could do. Any ideas? I'm thinking at least there must be a PowerShell script I could run on bootup that performs the switch each time.