Backup failing with inconsistency

We have been has an issue with our server backup taking a long time and failing with inconsistency.  The total backup of around 600GB and we are backing up to USB external 1TB drives.  We run a full backup starting on Saturday and it doesn't finish until Monday and then run incremental the other days.  
I am looking for suggestions on what I should do to resolve this error and possibly speed it up.  I was thinking that maybe I could split the full backup into several backups.  We have a C:\ and a D:\.  The D:\ contains two main directories for files sharing and a Program Files directory.  

Please let me know your options.  Thanks

PS:  Here is the last Full backup log and the command that runs it:

Backup Status
Operation: Backup
Active backup destination: File
Media name: "FullBackup.bkf created 12/17/2011 at 5:00 PM"

Volume shadow copy creation: Attempt 1.
Backup (via shadow copy) of "C: OS"
Backup set #1 on media #1
Backup description: "Set created 9/23/2009 at 2:09 PM"
Media name: "FullBackup.bkf created 12/17/2011 at 5:00 PM"

Backup Type: Normal

Backup started on 12/17/2011 at 5:15 PM.
Backup completed on 12/17/2011 at 5:56 PM.
Directories: 5627
Files: 35853
Bytes: 17,083,788,853
Time:  40 minutes and  35 seconds
Backup (via shadow copy) of "D: DATAPART1"
Backup set #2 on media #1
Backup description: "Set created 9/23/2009 at 2:09 PM"
Media name: "FullBackup.bkf created 12/17/2011 at 5:00 PM"

Backup Type: Normal

Backup started on 12/17/2011 at 5:56 PM.
Warning: Unable to open "D:\Public\Brad\Stuff from old Dell\Downloads\SetupGamevance (1).exe" - skipped.
Reason: Access is denied.


Warning: Unable to open "D:\Public\Brad\Stuff from old Dell\Downloads\SetupGamevance (2).exe" - skipped.
Reason: Access is denied.


Warning: Unable to open "D:\Public\Brad\Stuff from old Dell\Downloads\SetupGamevance (3).exe" - skipped.
Reason: Access is denied.



Error: An inconsistency was encountered in the requested backup file.
The operation was ended.
Backup completed on 12/19/2011 at 12:01 PM.
Directories: 59241
Files: 425829
Bytes: 595,214,660,469
Time:  1 day,  18 hours,  5 minutes, and  29 seconds

Error: D: is not a valid drive, or you do not have access.

The operation was ended.
Backup completed on 12/19/2011 at 12:01 PM.
Directories: 59241
Files: 425829
Bytes: 595,214,660,469
Time:  1 day,  18 hours,  5 minutes, and  41 seconds

----------------------

The operation did not successfully complete.

----------------------

C:\WINDOWS\system32\ntbackup.exe backup "@C:\Documents and Settings\backup\Local Settings\Application Data\Microsoft\Windows NT\NTBackup\data\Full.bks" /n "FullBackup.bkf created 9/23/2009 at 2:09 PM" /d "Set created 9/23/2009 at 2:09 PM" /v:yes /r:no /rs:no /hc:off /m normal /j "Full" /l:s /f "G:\FullBackup.bkf"
DCS12Asked:
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shahzoorCommented:
run scandisk function at boot and restart the server
Then run the task again
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DCS12Author Commented:
What will this do to help?  Would this take a long time?  I do need to be onsite or could it be done remote?
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shahzoorCommented:
yes u can do it remotely
Better to do it in off peak hours
it can take some time depending on the bad sectors or locked files on your hard disk
Once the server will restart the backup function will work smoothly
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DCS12Author Commented:
My other concern is that the backup is running until Monday morning or afternoon when users are logged on a using the files.  What you are suggesting won't speed up the process, will it?
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shahzoorCommented:
I wouldn't rely on windows backup for that.
We use acronis backuo and recovery and we can define the backup tasks easily.
Even there are options of full backup or incremental backup. So the backup process does not take that much time.
Further you can define the backup speed and time etc.
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DCS12Author Commented:
What exactly do you mean "rely on windows backup for that"?  For running backups or backups while files are in use.  

I looked at Acronis and it looks like the Acronis® Backup & Recovery™ 11 Server for Windows would be what we need.  Is this what you use?      
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shahzoorCommented:
Yes we are using it and i never had any problems
We prefer using third party products if they are more professional and satisfying our needs. I never used windows Backup so i dont rely on it  :)
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