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Files mysteriously disappearing from drive

Last Modified: 2013-11-22
I'm working on a customers laptop, his complaint is files keep disappearing from the hard drive.  I've run antispyware/virus scans removed several infected files.  I still have a problem with files disappearing from the system.  I was copying antispyware files from my flash drive to the desktop.  The file would copy and the icon show up on the desktop but before I could double click on the file to install the icon would disappear.  I've looked everywhere on the drive, ran msconfig and disabled everything, booted to safe mode.  The file has just vanished.  I've been searching the web for any virus or spyware that might be causing this but have found nothing.  Any ideas?
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