Remote Desktop Services, Terminal Server, Restrict user programs

I have a windows 2008 r2 server and I want to restrict all users but two to a certain program.  I want to allow the other two users full access.  

Is it best done via a loopback policy or some other way?
bhgewilsonAsked:
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jerseysamCommented:
Yes i would definately use GPO and loopback.
http://support.microsoft.com/default.aspx?scid=kb;en-us;231287

Other ways are very cumbersome ie. changing the security properties on Applications in Program Files to allow certain users/groups access.

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Windows Server 2008

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