A few days ago, I think I had a Skype update. I noticed yesterday that while Skype was in my task manager, it didn't give me a screen to work with and nothing in the bottom right corner of my screen to pull Skype up.
I killed it, went to the Skype website and downloaded a new installation. It ran all night spinning on the "please wait".
I then tried to uninstall it, and it stuck on "Preparing to Uninstall". I now find that I can't install or uninstall anything (I tried the MSFT fix it and its been spinning for a few hours as well):
While it appeared to install via another method than I've seen in a while, it asked me whether I was having install or uninstall problems. I advised Uninstall, selected the app after being prompted, and now its spinning on "Resolving problems - Corrupt Patch Registry Keys"
I have Windows Vista Home Premium SP2 32 bit OS installed.